LFB in the world

LFB works with its subsidiaries and partners to market its medicinal products in some thirty countries worldwide.

LFB has decided to implement a selective strategy outside of France, by focusing its efforts on 8 markets offering growth potential​ for its key medicinal products: Belgium, Germany, Italy, Mexico, Spain, Turkey, the United Kingdom and the United States of America.
  • About fifteenbiomedicinal products marketed worldwide

  • A row of transparent bottles with an undefined container on a production line.
  • 41% of LFB’s sales are booked outside France

  • Several flags of different countries flying in the wind.

France

France - detailed description below

A major economic and industrial player in France

With about fifteen biomedicinal products on the market, LFB is a major player in France for health professionals in hospitals.
LFB’s medicinal products are used to treat hundreds of thousands of patients each year, for both chronic care and in emergency situations.

With 2,200 employees in France, 5 industrial sites, the Group’s head office and development teams, LFB is a major economic player in health.
The Operations France teams provide hospital teams with innovative technological tools to raise awareness of certain rare and serious pathologies.

Commitment to healthcare professionnals

  • Alès (30)
  • Arras (62)
  • Carvin (62)
  • Lille (59)
  • Les Ulis (91)

Blood products, including plasma, are collected in France by a single operator: the Etablissement Français du Sang (EFS).

In France, donations of plasma, blood and platelets are voluntary, anonymous, unpaid and uncompensated.

To know more about EFS

Thanks to its CDMO status (Contract Development and Manufacturing Organization), and approved by the FDA (Food and Drug Administration), the Alès site shares its know-how and equipment with its customers, including support from the development of cell lines and industrial-scale processes to the manufacture of clinical and commercial batches, as well as the associated analytical testing. It is one of LFB’s key entities specialising in the bioproduction of therapeutic proteins, in particular monoclonal antibodies, by cell culture.

The Arras site is a new generation plant that houses all of the production steps for immunoglobulins, fibrinogen and albumin.
Commissioned at the end of 2024, this plant will enable LFB to triple its production capacity.
With this € 750 million investment, LFB will make a real technological leap forward.

The Carvin site (Pas-de-Calais department, France) offers a warehouse to store the materials needed to produce medicinal products for the Lille plant.
It is also the packaging site for LFB’s liquid products.

The Lille plant (North department, France) specialises in the downstream steps of the production processes for plasma-derived medicinal products, from the intermediate products to aseptic filling.

The Les Ulis plant (Essonne department, France) specialises in the upstream steps of the production processes for plasma-derived medicinal products, from receipt of the bags of plasma to the intermediate products.
LFB’s head offices are located in Paris.

Europe

Europe - detailed description below

A leader in Europe

LFB has a foothold in various European countries for the marketing of its plasma-derived medicinal products, notably with the presence of subsidiaries in key countries such as Belgium, Germany, Spain and the United Kingdom.
LFB also works to expand its plasma collection network in Europe with 25 plasma and blood collection centres, with the goal of ensuring a continuous supply of plasma to manufacture its medicinal products.

In Europe, LFB has chosen to concentrate its efforts on five countries with growth potential for its key medicinal products.

Today, LFB markets biomedicinal products in around a dozen European countries, with the support of its subsidiaries and commercial partners.

  • Austria
  • Finland
  • Greece
  • Hungary
  • Lithuania
  • Luxembourg
  • Netherlands
  • Poland
  • Slovakia
  • Slovenia
  • Switzerland

EUROPLASMA, a subsidiary of LFB, manages 25 plasma and blood collection centres in Europe:

  • 15 centres in the Czech Republic,
  • 9 centres in Austria,
  • 1 centre in Germany, opened since Novembre 2024.

The LFB is thus committed to increasing its plasma collection capacity in order to meet the growing demand from patients in Europe. Securing a continuous supply of plasma is a major public health issue.

Americas

Americas - detailed description below

LFB has been established in Americas for many years, with a bioproduction site, plasma and blood collection centres and products already on the market.

Located in the state of Massachusetts in the United States of America, the Charlton plant specialises in the production of recombinant proteins developed on its rPRO™ technological platform. This technology consists of expressing the desired protein of interest in mammalian milk by genetic recombination.

LFB and its American subsidiary LFB Plasma manage 6 plasma collection centres in the United States of America: in Alabama, Colorado, Florida, North Carolina and South Carolina.

In accordance with US FDA requirements, Food and Drug Administration, only medicinal products derived from plasma donated in the USA can be sold in the USA.

LFB markets recombinant activated factor VII in the United States of America for the treatment of certain rare haemophilia disorders.
LFB is also present in Mexico, through its subsidiary LFB MEXICO responsible for the marketing of several plasma-derived medicinal products, and in Colombia.

Worldwide locations​

Worldwide locations - detailed description below

Today, LFB markets biomedicinal products with the support of its subsidiaries and commercial partners.

Turkey is a key growth country selected by LFB for the marketing of its key medicinal products.

Today, LFB markets biomedicinal products in around a dozen European countries, with the support of its subsidiaries and commercial partners.

  • Algeria
  • Kuwait
  • Lebanon
  • Morocco
  • Tunisia
  • United Arab Emirates